Structure of PDB 7xye Chain A

Receptor sequence
>7xyeA (length=481) Species: 285500 (Streptomyces luteocolor) [Search protein sequence]
TDVIVVGNGVLGLSVGVEIARTRPDVRVTLLGKPARQYGATPAAGAMLGA
FGEVTAHALASEHGRKKHALAVQAQRLWPEWIESLEATGTAADGRIKTAD
DTVVLLNTVGHSALDDANFAAVLTALKEANAPHEEIAVESVDWIDPDPNS
RPLRALHIEGEGSVDSGILLAALERSFLQAGGRLHPVDATEIRASHGRVE
GVVTDDGDFLPAGHVVVAAGARSQRLVAALPGLAHRIPRIYDGVGVSALV
DTWDGSGPATVLRTSNRAFACGLHLVPRAGGSVYIGATNAVCLEPRGAAS
IEETVFLFNCATHQLHRGLNGSELRKVQVGSRPAPIDGFPLIGGTSVEGL
WMLSGTYRDGLHMSPLLARHVVSLMDGGTGVDGLREFRPERDLISAWSRE
EILDDVVRHTMATGYEFPWRLPLEWPHMMETFLQGPFAELADRLSDTYTP
PADLMTAIMFSEREQQDELIAYYADVHREWH
3D structure
PDB7xye N-Formimidoylation/-iminoacetylation modification in aminoglycosides requires FAD-dependent and ligand-protein NOS bridge dual chemistry.
ChainA
Resolution2.482 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD A V16 G17 N18 G19 L21 G42 R46 Q47 G49 A50 T51 A54 M57 D198 A199 A229 G230 R232 G255 G340 R342 T366 Y367 R368 D369 G370 L371 H372 V6 G7 N8 G9 L11 G32 R36 Q37 G39 A40 T41 A44 M47 D188 A189 A219 G220 R222 G245 G330 R332 T356 Y357 R358 D359 G360 L361 H362
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:7xye, PDBe:7xye, PDBj:7xye
PDBsum7xye
PubMed37137912
UniProtA0A125SZC1

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