Structure of PDB 7xyd Chain A

Receptor sequence
>7xydA (length=129) Species: 9606 (Homo sapiens) [Search protein sequence]
GIECDSCINPSNWCDGVSHCPGGEDENRCVRLYGPNFILQVYSSQRKSWH
PVCQDDWNENYGRAACRDMGYKNNFYSSQGIVDDSGSTSFMKLNTSAGDI
YKKLYHSDACSSKAVVSLRCIACGVNLND
3D structure
PDB7xyd Crystal structure of TMPRSS2 in complex with Nafamostat
ChainA
Resolution2.58 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.21.122: transmembrane protease serine 2.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA A N131 D134 V136 H138 D144 E145 N12 D15 V17 H19 D25 E26
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:7xyd, PDBe:7xyd, PDBj:7xyd
PDBsum7xyd
PubMed37990007
UniProtO15393|TMPS2_HUMAN Transmembrane protease serine 2 (Gene Name=TMPRSS2)

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