Structure of PDB 7xxv Chain A

Receptor sequence
>7xxvA (length=136) Species: 9541 (Macaca fascicularis) [Search protein sequence]
MQVPHTESVSLSAGSTVTIKGRPLVCFFNEPHLQVDFHTEMKEDSDIAFH
FQVYFGNRVVMNSREFKIWKEEVESKNMPFQDGQEFELSILVLEDKYQVM
VNGQAYYNFNHRIPVSSVKMVQVWRDISLTKFNVSN
3D structure
PDB7xxv Glutathione disrupts galectin-10 Charcot-Leyden crystal formation to possibly ameliorate eosinophil-based diseases such as asthma.
ChainA
Resolution1.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 BGC A R61 E75 R58 E72
BS02 GAL A H53 N65 W72 E75 H50 N62 W69 E72
Gene Ontology
Molecular Function
GO:0030246 carbohydrate binding
Cellular Component
GO:0062023 collagen-containing extracellular matrix

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Molecular Function
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Cellular Component
External links
PDB RCSB:7xxv, PDBe:7xxv, PDBj:7xxv
PDBsum7xxv
PubMed36988350
UniProtG7PXK5

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