Structure of PDB 7xwr Chain A

Receptor sequence
>7xwrA (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
LSPEQLVLTLLEAEPPHVLISREASMMMSLTKLADKELVHMISWAKKIPG
FVELSLFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGK
SVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSDSSRKLAHL
LNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM
KSKNVVPVYDLLLEMLNAH
3D structure
PDB7xwr Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives.
ChainA
Resolution2.164 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I310 K314 V328 E493 I42 K46 V60 E214
BS02 I2B A L298 T299 E305 L339 F356 H475 L476 L30 T31 E37 L71 F88 H196 L197
External links
PDB RCSB:7xwr, PDBe:7xwr, PDBj:7xwr
PDBsum7xwr
PubMed35810932
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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