Structure of PDB 7xwp Chain A

Receptor sequence
>7xwpA (length=219) Species: 9606 (Homo sapiens) [Search protein sequence]
LSPEQLVLTLLEAEPPHVLISREASMMMSLTKLADKELVHMISWAKKIPG
FVELSLFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGK
SVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSDSSRKLAHL
LNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNM
KSKNVVPVYDLLLEMLNAH
3D structure
PDB7xwp Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives.
ChainA
Resolution1.919 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I310 K314 V328 E493 I42 K46 V60 E214
BS02 I1I A M295 E305 M340 F356 H475 L476 M27 E37 M72 F88 H196 L197
External links
PDB RCSB:7xwp, PDBe:7xwp, PDBj:7xwp
PDBsum7xwp
PubMed35810932
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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