Structure of PDB 7xvz Chain A

Receptor sequence
>7xvzA (length=218) Species: 9606 (Homo sapiens) [Search protein sequence]
LSPEQLVLTLLEAEPPHVLISEASMMMSLTKLADKELVHMISWAKKIPGF
VELSLFDQVRLLESSWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKS
VEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSDSSRKLAHLL
NAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMK
SKNVVPVYDLLLEMLNAH
3D structure
PDB7xvz Evaluating the correlation of binding affinities between isothermal titration calorimetry and fragment molecular orbital method of estrogen receptor beta with diarylpropionitrile (DPN) or DPN derivatives.
ChainA
Resolution2.08 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I310 K314 V328 I41 K45 V59
BS02 I1D A M295 L298 T299 E305 L339 F356 H475 L476 M26 L29 T30 E36 L70 F87 H195 L196
External links
PDB RCSB:7xvz, PDBe:7xvz, PDBj:7xvz
PDBsum7xvz
PubMed35810932
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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