Structure of PDB 7xty Chain A

Receptor sequence
>7xtyA (length=89) Species: 9606 (Homo sapiens) [Search protein sequence]
GDIFEVELAKNDNSLGISVTGGVNTSVRHGGIYVKAVIPQGAAESDGRIH
KGDRVLAVNGVSLEGATHKQAVETLRNTGQVVHLLLEKG
3D structure
PDB7xty Targeting PTPN13 with 11 amino acid peptides of C-terminal APC prevents immune evasion of colorectal cancer
ChainA
Resolution2.1 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A S1377 L1378 I1380 S1381 V1382 T1383 K1398 H1431 V1435 S14 L15 I17 S18 V19 T20 K35 H68 V72
External links
PDB RCSB:7xty, PDBe:7xty, PDBj:7xty
PDBsum7xty
PubMed
UniProtQ12923|PTN13_HUMAN Tyrosine-protein phosphatase non-receptor type 13 (Gene Name=PTPN13)

[Back to BioLiP]