Structure of PDB 7xt7 Chain A

Receptor sequence
>7xt7A (length=1404) Species: 460519 (Komagataella phaffii) [Search protein sequence]
SQFPYSSAPLRSVKEVQFGLLSPEEIRAISVVKIEYPEIMDESRQRPREG
GLNDPKLGSIDRNFKCQTCGEGMAECPGHFGHMELAKPVFHIGFIPKIKK
VCECICMNCGKLLLDETNPTMAQAIRIRDPKKRFNAVWQLCKTKMVCEAD
APVSRGGCGNTQPVVRKDGMKLWGTWKKSRDAQPERKLLTPGEILNVFKH
ISPEDCFRLGFNEDYARPEWMIITVLPVPPPQVRPSIAMDETTQGQDDLT
HKLSDILKANINVQKLEMDGSPQHIINEVEQLLQFHVATYMDNDIAGQPQ
ALQKSGRPVKAIRARLKGKEGRLRGNLMGKRVDFSARTVISGDPNLELDQ
VGVPISIAKTLSYPETVTQYNIHRLTEYVRNGPNEHPGAKYVIRDNGDRI
DLRYHKRAGDIVLQYGWKVERHLMDDDPVLFNRQPSLHKMSMMAHRVKVM
PYSTFRLNLSVTSPYNADFDGDEMNLHVPQSEETRAELSQLCAVPLQIVS
PQSNKPVMGIVQDTLCGVRKMTLRDTFIEYEQVMNMLFWVPSWDGVVPQP
AILKPKPLWTGKQLLSIAIPSGIHLQRTDGGNSLLSPKDNGMLIVDGKVM
FGVVDKKTVGSGGGGLIHTVMREKGPKICAELFGNIQKVVNYWLLHNGFS
IGIGDAIADASTMKEITHAISSAKEQVQEIIYKAQHNELELKPGMTLRES
FEGEVSRTLNDARDSAGRSAEMNLKDLNNVKQMVSAGSKGSFINIAQMSA
CVGQQMVEGKRIAFGFADRSLPHFTKDDFSPESKGFVENSYLRGLTPQEF
FFHAMAGREGLIDTAVKTAETGYIQRRLVKALEDIMVHYDGTTRNSLGDI
IQFLYGEDGLDGTQVERQTIDTIPGSDKAFHKRYYVDLMDEKNSIKPDVI
EYAADILGDVELQKELNSEYEQLVSDRKFLREIVFVNGDHNWPLPVNLRR
IIQNAQQIFHLDRAKASDLTIPEIIHGVRDLCKKLFVLRGENELIKEAQQ
NATSLFQCLVRARLATRRILEEFRLNRDAFEWVLGTIEAQFQRSLVHPGE
MVGVIAAQSIGEPATQMNVTLGVPRLKEILNVAKNIKTPALTVYLDREIA
LDIEKAKVIQSSIEYTTLKNVTSATEIYYDPDPTSTVIEEDFDTVEAYFS
QSPWLLRLELDRARMLDKQLTMNQVADKISEVFSDDLFVMWSEDNADKLI
IRCRVIEEDQMLKRIEAHMLDLIALRGIPGISKVYMVKHKVSVPDESGEY
KNEELWALETDGINLAEVMAVPGVDSSRTYSNSFVEILSVLGIEATRSSL
YKEILNVIAFDGSYVNYRHMALLVDVMTSRGYLMAITRHGINRADTGALM
RCSFEETVEILFEAGAAAELDDCRGVSENVMLGQLAPMGTGAFDVMIDEK
LLTS
3D structure
PDB7xt7 Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
ChainA
Resolution4.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005634 nucleus
GO:0005665 RNA polymerase II, core complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xt7, PDBe:7xt7, PDBj:7xt7
PDBsum7xt7
PubMed35981082
UniProtC4R4Y0

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