Structure of PDB 7xs7 Chain A

Receptor sequence
>7xs7A (length=729) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
FKLWNGNFVFDSPISKTLLDQYATTTENANTLPNEFKFMRYQAVTCEPNQ
LAEKNFTVRQLKYLTPRETELMLVVTMYNEDHILLGRTLKGIMDNVKYMV
KKKNSSTWGPDAWKKIVVCIISDGRSKINERSLALLSSLGCYQDGFAKDE
INEKKVAMHVYEHTTMINITNISESEVSLECNQGTVPIQLLFCLKEQNQK
KINSHRWAFEGFAELLRPNIVTLLDAGTMPGKDSIYQLWREFRNPNVGGA
CGEIRTDLGKRFVKLLNPLVASQNFEYKMSNILDKTTESNFGFITVLPGA
FSAYRFEAVRGQPLQKYFYGEGFHFFSSNMYLAEDRILCFEVVTKKNCNW
ILKYCRSSYASTDVPERVPEFILQRRRWLNGSFFASVYSFCHFYRVWSSG
HNIGRKLLLTVEFFYLFFNTLISWFSLSSFFLVFRILTVSIALAYHSAFN
VLSVIFLWLYGICTLSTFILSLGNKPKSTEKFYVLTCVIFAVMMIYMIFC
SIFMSVKSFQNILKTEAFRDIVISLGSTYCLYLISSIIYLQPWHMLTSFI
QYILLSPSYINVLNIYAFCNVHDLSWGTKGAMANPLGKINTTEDGTFKME
VLVSSSEIQANYDKYLKVLNDFDPKSESRPTEPSYDEKKTGYYANVRSLV
IIFWVITNFIIVAVVLETGGIADYIAMKSISTAEIPLMTSKASIYFNVIL
WLVALSALIRFIGCSIYMIVRFFKKVTFR
3D structure
PDB7xs7 structure of a membrane-integrated glycosyltransferase with inhibitor
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.4.1.16: chitin synthase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 0V9 A F1052 G1062 F659 G669
Gene Ontology
Molecular Function
GO:0004100 chitin synthase activity
GO:0016757 glycosyltransferase activity
GO:0016758 hexosyltransferase activity
Biological Process
GO:0000920 septum digestion after cytokinesis
GO:0006031 chitin biosynthetic process
GO:0071555 cell wall organization
Cellular Component
GO:0005886 plasma membrane
GO:0030428 cell septum
GO:0045009 chitosome
GO:0071944 cell periphery

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7xs7, PDBe:7xs7, PDBj:7xs7
PDBsum7xs7
PubMed
UniProtP08004|CHS1_YEAST Chitin synthase 1 (Gene Name=CHS1)

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