Structure of PDB 7xr7 Chain A

Receptor sequence
>7xr7A (length=493) Species: 68268 (Streptomyces showdoensis) [Search protein sequence]
ATAVVRCRTRLARRVVAAVGPDGLLPAPCESRVLESALALALLTEERAEA
DATARLTAYLRTTLRTAPPDPFQCAVARAVLGDAGTALDAGLDGFDHFTA
GRKRLMFRTVLAALGATGFPAVPWEAYDTRPQQSWLHMEMKALKVLAAHG
TGHPDVVRDEDWRALLPALEPGPAWECNNLAQLLALLALRHSPRHRPALG
DVLKHVAGRLRPDGGMPFIDGMTVFTTAAAGLALSLLPAPPACVTPMADA
LALRRNPDGGYGFHSGVAQSDVEDTCYVLEFLRRAAPDRHRTAVAEAEGY
LLALRNPDGGFPTFARGTSSEIAMTAAAASALAHDPDRREEVDEAVRYVV
RHQRPDGTFERSWSRNATNAVFRAVLALTGVAAHGEERRSRARAAERALA
HLAATQNGDGGWGHAEAEPSDPISTAYAVIALARGPRARPGGPLDRALAY
LVERQHPDGGYRSRPDQAGPRPLLYDVPALADVFVLLALAHAT
3D structure
PDB7xr7 Discovery, Structure, and Mechanism of a Class II Sesquiterpene Cyclase.
ChainA
Resolution1.63 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FPP A R132 K133 Q163 W165 F248 M252 F255 F293 D301 E303 W393 Q497 P500 R501 Y505 R102 K103 Q133 W135 F218 M222 F225 F263 D271 E273 W363 Q467 P470 R471 Y475
BS02 MG A W165 E169 N208 F248 W135 E139 N178 F218
BS03 MG A E169 P500 E139 P470
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0016866 intramolecular transferase activity
GO:0046872 metal ion binding
Biological Process
GO:0008610 lipid biosynthetic process
GO:0016104 triterpenoid biosynthetic process
Cellular Component
GO:0005811 lipid droplet

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xr7, PDBe:7xr7, PDBj:7xr7
PDBsum7xr7
PubMed36416740
UniProtA0A2P2GK84

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