Structure of PDB 7xpx Chain A

Receptor sequence
>7xpxA (length=99) Species: 8355 (Xenopus laevis) [Search protein sequence]
KKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQ
SSAVMALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGER
3D structure
PDB7xpx Structural basis of nucleosomal H4K20 methylation by methyltransferase SET8.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A K36 Y41 G44 V46 A47 R49 R63 K64 L65 P66 R69 R83 K1 Y6 G9 V11 A12 R14 R28 K29 L30 P31 R34 R48
BS02 dna A R42 T45 R63 R72 R83 F84 Q85 S86 R116 V117 T118 R7 T10 R28 R37 R48 F49 Q50 S51 R81 V82 T83
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7xpx, PDBe:7xpx, PDBj:7xpx
PDBsum7xpx
PubMed35532550
UniProtP84233|H32_XENLA Histone H3.2

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