Structure of PDB 7xpl Chain A

Receptor sequence

>7xplA (length=375) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]

KIYLIEHVIGAVAYDENGNIVDYITNPRDLGKITEELLNNEKGIPFSATV
ELLKKVNPQEVVVENEAEVPKLQALGYRVSYEPYSKVSRIFRESLPKVAI
DIKFASNEEDYYNFLHELSLEYTRRKLRSAAQKRDLLAIQAVRAMDDIDK
TINLFSERLREWYSIHFPELDKLIEDHEEYATIVSRFGDRGFLTIDSLKE
LGFNEQRINRILDAAKKSIGADISEDDLSAMRMIANTILDLYNIRRNLNN
YLEGVMKEVAPNVTALVGPALGARLLSIAGSLDELAKMPASTIQVLGAEK
ALFRALRSGGRPPKHGIIFQYPAIHTSPRWQRGKIARALAAKLAIAARVD
AFSGRFIGDQLNEQLKKRIDEIKEK

3D structure

PDB

7xpl Methylation guide RNAs without box C/D motifs.

Chain

Resolution

2.213 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	rna	A	R145 L304 F305	R143 L302 F303
BS02	rna	A	K152 E159 R160 Q296 A300 K302 A303 R306 R313 P314 P315 K316 H317 G318 F321 K336 R339	K150 E157 R158 Q294 A298 K300 A301 R304 R311 P312 P313 K314 H315 G316 F319 K334 R337
BS03	rna	A	K302 F305	K300 F303
BS04	rna	A	N155 E159 H179 R276 F321 Q322 H327	N153 E157 H177 R274 F319 Q320 H325

Gene Ontology

	Molecular Function
GO:0005515	protein binding
GO:0030515	snoRNA binding

	Cellular Component
GO:0031428	box C/D methylation guide snoRNP complex
GO:0032040	small-subunit processome

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Molecular Function

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Cellular Component

External links

PDB	RCSB:7xpl, PDBe:7xpl, PDBj:7xpl
PDBsum	7xpl
PubMed	36127125
UniProt	Q97ZH3

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