Structure of PDB 7xna Chain A

Receptor sequence
>7xnaA (length=472) Species: 1397,9606 [Search protein sequence]
TSNAVLTFIYFVVCIIGLCGNTLVIYVILRYAKMKTITNIYILNLAIANE
LFMLGLPFLAMQVALEHWPFGKAICRVVMTVDGINQFTSIFCLTVMSIDR
YLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIYAGLRSNQWGR
SSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSAST
DYWQNWTFGGGIVNAVNGSGGNYSVNWSNTGNFVVGKGWTTGSPFRTINY
NAGVWAPNGNGYLTLYGWTRSPLIEYYVVDSWGTYRPTGTYKGTVKSDGG
TYDIYTTTRYNAPSIDGDDTTFTQYWSVRQSKRPTGSNATITFTNHVNAW
KSHGMNLGSNWAYQVMATEGYQSSGSSNVTVWSSKRKKSEKKVTRMVSIV
VAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVLTYANSCANPIL
YAFLDDNFKKSFQNVLCLVKVS
3D structure
PDB7xna Structural insights into ligand recognition and selectivity of somatostatin receptors.
ChainA
Resolution2.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.8: endo-1,4-beta-xylanase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A N43 E106 M119 D122 Q126 T194 Y205 F275 M282 P286 L290 K291 F294 D295 V298 N3 E66 M79 D82 Q86 T154 Y165 F414 M421 P425 L429 K430 F433 D434 V437
Gene Ontology
Molecular Function
GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0004930 G protein-coupled receptor activity
GO:0004994 somatostatin receptor activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0031176 endo-1,4-beta-xylanase activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0045493 xylan catabolic process
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xna, PDBe:7xna, PDBj:7xna
PDBsum7xna
PubMed35739238
UniProtP09850|XYNA_NIACI Endo-1,4-beta-xylanase (Gene Name=xlnA);
P30874|SSR2_HUMAN Somatostatin receptor type 2 (Gene Name=SSTR2)

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