Structure of PDB 7xm0 Chain A

Receptor sequence

>7xm0A (length=258) Species: 1280 (Staphylococcus aureus) [Search protein sequence]

MKEKSIEDIVFEKFQPYINWSIDKLCEHFSINKGEKGLNYRIASAILNLK
GKTTKSKPFPEVEEFEKSSIVVKTVHFNKKNVNKESMSFGAFKFEELANE
EWEDSEGYPSAQWRNFLLETRFLFFVVKEDEDGVDIFKGIKFFSMPEEDI
NGPVKRMWDDTVKKLKEGVTLEAVPDKSTKDGWRIKNNFVDKSDDLICHV
RPHTNNRDYRGGSNADKLPKKINWINRPDSDDYSDEWMTKQSFWINNDYI
KKQVEDLL

3D structure

PDB

7xm0 The Self-Activation Mechanism of Type IIE Restriction Endonuclease Sau3AI

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	dna	A	K267 Y271 K304 T305 E316 S319 S409 H434 T435 N436 K471 W475	K36 Y40 K73 T74 E85 S88 S178 H203 T204 N205 K240 W244
BS02	dna	A	E266 K267 R272 I416 K417 N418 D422 K423 S424 R432 P433 T435 N436 N437 R438 Y440	E35 K36 R41 I185 K186 N187 D191 K192 S193 R201 P202 T204 N205 N206 R207 Y209
BS03	MG	A	N418 D422	N187 D191

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity

View graph for
Molecular Function

External links

PDB	RCSB:7xm0, PDBe:7xm0, PDBj:7xm0
PDBsum	7xm0
PubMed
UniProt	P16667\|T2S3_STAAU Type II restriction enzyme Sau3AI (Gene Name=sau3AIR)

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