Structure of PDB 7xi4 Chain A

Receptor sequence
>7xi4A (length=283) Species: 10090 (Mus musculus) [Search protein sequence]
SSADKERLARENHSEIERRRRNKMTAYITELSDMVPTCSALARKPDKLTI
LRMAVSHMKSLRGTGNKPSFLTDQELKHLILEAADGFLFIVSCETGRVVY
VSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSGSRRSFICRM
RCGTSSFVVVHCTGYIKAFCLVAIGRLQVTEFISRHNIEGIFTFVDHRCV
ATVGYQPQELLGKNIVEFCHPEDQQLLRDSFQQVVKLKGQVLSVMFRFRS
KTREWLWMRTSSFTFQNPYSDEIEYIICTNTNV
3D structure
PDB7xi4 Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
ChainA
Resolution4.707 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A R91 H94 E98 R102 D127 K128 R10 H13 E17 R21 D46 K47
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xi4, PDBe:7xi4, PDBj:7xi4
PDBsum7xi4
PubMed36343253
UniProtP53762|ARNT_MOUSE Aryl hydrocarbon receptor nuclear translocator (Gene Name=Arnt)

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