Structure of PDB 7xhv Chain A

Receptor sequence
>7xhvA (length=177) Species: 10090 (Mus musculus) [Search protein sequence]
DKERLARENHSEIERRRRNKMTAYITELSDMVPTCSAARKPDKLTILRMA
VSHMKSLRGPSFLTDQELKHLILEAADGFLFIVSCETGRVVYVSDSVTPV
LNQPQSEWFGSTLYDQVHPDDVDKLREQLSTSGSRRSFICRMRCGTSSVF
VVVHCTGYIKAWPPAGFCLVAIGRLQV
3D structure
PDB7xhv Structures of NPAS4-ARNT and NPAS4-ARNT2 heterodimers reveal new dimerization modalities in the bHLH-PAS transcription factor family.
ChainA
Resolution3.996 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna A H94 R99 R102 D127 K128 H10 R15 R18 D42 K43
BS02 dna A H94 I97 E98 R101 H10 I13 E14 R17
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7xhv, PDBe:7xhv, PDBj:7xhv
PDBsum7xhv
PubMed36343253
UniProtP53762|ARNT_MOUSE Aryl hydrocarbon receptor nuclear translocator (Gene Name=Arnt)

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