Structure of PDB 7xhe Chain A

Receptor sequence
>7xheA (length=121) Species: 9606 (Homo sapiens) [Search protein sequence]
GHHHHHKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYF
DIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYK
FCSKLAEVFEQEIDPVMQSLG
3D structure
PDB7xhe Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain
ChainA
Resolution1.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.48: histone acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 JHF A P1110 Q1113 V1115 Y1167 N1168 V1174 F1177 P34 Q37 V39 Y91 N92 V98 F101
Gene Ontology
Molecular Function
GO:0004402 histone acetyltransferase activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7xhe, PDBe:7xhe, PDBj:7xhe
PDBsum7xhe
PubMed
UniProtQ92793|CBP_HUMAN CREB-binding protein (Gene Name=CREBBP)

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