Structure of PDB 7xen Chain A

Receptor sequence
>7xenA (length=392) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
MNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNA
TDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVALSYARANLKPGDE
VVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTISLEDVRETVTSNT
KIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQSTPHMKIDVQDL
DCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFGGEMIDFVGLYEST
WKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEISRHEHKLAAYALER
FRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDAEGIAVRAGHHCAQ
PLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKEYFTNV
3D structure
PDB7xen X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
ChainA
Resolution2.47 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 9ZN A A28 A29 T92 T93 H121 N173 D198 A200 Q201 S221 K224 H360 R376 A28 A29 T79 T80 H108 N160 D185 A187 Q188 S208 K211 H347 R363
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0006534 cysteine metabolic process

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7xen, PDBe:7xen, PDBj:7xen
PDBsum7xen
PubMed
UniProtO32164|SUFS_BACSU Cysteine desulfurase SufS (Gene Name=sufS)

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