Structure of PDB 7xej Chain A

Receptor sequence
>7xejA (length=413) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence]
MNITDIREQFPILHQQVNGHDLVYLDSAATSQKPRAVIETLDKYYNQYNS
NVHRGVHTLGTRATDGYEGAREKVRKFINAKSMAEIIFTKGTTTSLNMVA
LSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGTI
SLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGA
QSTPHMKIDVQDLDCDFFALSSHKMCGPTGVGVLYGKKALLENMEPAEFG
GEMIDFVGLYESTWKELPWKFEAGTPIIAGAIGLGAAIDFLEEIGLDEIS
RHEHKLAAYALERFRQLDGVTVYGPEERAGLVTFNLDDVHPHDVATVLDA
EGIAVRAGHHCAQPLMKWLDVTATARASFYLYNTEEEIDKLVEALQKTKE
YFTNVFVDLEHHH
3D structure
PDB7xej X-ray crystallographic snapshots of the thioazolidine formation upon the PLP during inhibition of SufS by D-cysteine
ChainA
Resolution1.74 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.8.1.7: cysteine desulfurase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 9PV A A28 A29 T92 T93 H121 N173 D198 A200 S221 H223 K224 R376 A28 A29 T92 T93 H121 N173 D198 A200 S221 H223 K224 R376
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0016740 transferase activity
GO:0030170 pyridoxal phosphate binding
GO:0031071 cysteine desulfurase activity
Biological Process
GO:0006534 cysteine metabolic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7xej, PDBe:7xej, PDBj:7xej
PDBsum7xej
PubMed
UniProtO32164|SUFS_BACSU Cysteine desulfurase SufS (Gene Name=sufS)

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