Structure of PDB 7xck Chain A

Receptor sequence

>7xckA (length=223) Species: 9606 (Homo sapiens) [Search protein sequence]

QVQLVQSGAEVKKPGASVKVSCKASGYPFTSYGISWVRQAPGQGLEWMGW
ISTYNGNTNYAQKFQGRVTMTTDTSTTTGYMELRRLRSDDTAVYYCARDY
TRGAWFGESLIGGFDNWGQGTLVTVSSASTKGPSVFPLAPSSKTAALGCL
VKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGT
QTYICNVNHKPSNTKVDKKVEPK

3D structure

PDB

7xck Omicron SARS-CoV-2 mutations stabilize spike up-RBD conformation and lead to a non-RBM-binding monoclonal antibody escape

Chain

Resolution

2.5 Å

3D
structure

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Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FUC	A	Y100 D115	Y100 D115

External links

PDB	RCSB:7xck, PDBe:7xck, PDBj:7xck
PDBsum	7xck
PubMed

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