Structure of PDB 7xc7 Chain A

Receptor sequence
>7xc7A (length=1191) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence]
MNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKAGKSFITG
TLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDESKGKKPSFLRKRHT
LQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSNFDLDN
DLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTGRITLRNEH
AKKLLLASLGFVDKLCGALCRIEVIHNDELRKQAEVIVEAFKQNDKLEKI
RILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQGTALRTKL
KELWQSNKDIGWRKFTEMLGSNLYLIYKKETGVSTRFRILGDTEYYSKAG
SDLFIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEKKEDS
LVINEHASFNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQI
LCNCKVCIEMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIE
VGPEGLTFPFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGK
GRFALKDIKIFEWDLNQKINEYIKERGMRGKEKELLEMGLPDGLIPYKFF
EERECLFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRAAIAY
KKRVYNDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTC
DMCIIFGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDK
AKFDTYPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPL
GSKGGVGYGWVAGISIDDNVPDDFKEMIGPINNDYVHPGHQSPKIYYPHY
FLDSGSKVYREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDENGL
KLQGNKPGHKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIFGED
STLKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAKYENG
PEWLITPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHNGWRIIRQK
QLEIRETVQPERNVTTEVMDKGNVFSFDVRFENLREWELGLLLQSLDPGK
NIAHKLGKGKPYGFGSVKIKIDSLHTFKIKRVPQSDIREYINKGYQKLIE
WVLPQWHVIPHIDKLYKLLWVPFLNDYKKLGDKDNLPYKTR
3D structure
PDB7xc7 Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E16 W23 R37 Q39 A40 F41 K47 K55 F57 T59 G60 T61 L62 R64 S65 K69 S91 F92 Q93 T94 E96 S103 F104 L105 R106 K107 R108 G134 R135 A139 G140 K141 H143 E144 Y149 F153 N155 D157 R176 I177 L178 N179 R180 V181 G186 K187 A188 D190 Y191 F192 K229 G232 L234 Y389 Y390 G431 R472 S473 A474 R476 G477 R481 V493 S494 L495 G496 G497 L500 R510 T513 L514 Y529 R530 I531 A532 K533 L545 F546 G592 G593 L594 S596 T684 A685 K723 E725 T726 R728 G729 I730 R732 N760 S765 D788 H789 V790 I792 R794 K804 G853 S854 K855 P967 S1001 E1002 R1004 G1005 R1008 I1021 G1421 T1422 T1423 Y1425 K1426 V1458 L1459 E1460 S1461 P1462 F1466 K1479 Y1481 G1550 K1551 K1553 E11 W18 R32 Q34 A35 F36 K42 K45 F47 T49 G50 T51 L52 R54 S55 K59 S81 F82 Q83 T84 E86 S93 F94 L95 R96 K97 R98 G124 R125 A129 G130 K131 H133 E134 Y139 F143 N145 D147 R161 I162 L163 N164 R165 V166 G171 K172 A173 D175 Y176 F177 K214 G217 L219 Y345 Y346 G383 R423 S424 A425 R427 G428 R432 V444 S445 L446 G447 G448 L451 R461 T464 L465 Y480 R481 I482 A483 K484 L496 F497 G543 G544 L545 S547 T632 A633 K671 E673 T674 R676 G677 I678 R680 N708 S713 D736 H737 V738 I740 R742 K752 G801 S802 K803 P892 S926 E927 R929 G930 R933 I946 G982 T983 T984 Y986 K987 V1015 L1016 E1017 S1018 P1019 F1023 K1036 Y1038 G1107 K1108 K1110
BS02 rna A K187 R294 K320 R323 H328 Y367 K371 S378 R382 S457 G543 L545 F546 E748 D749 E761 H762 D801 K802 A803 K804 F805 K985 R1505 K172 R251 K277 R280 H285 Y324 K328 S334 R338 S408 G494 L496 F497 E696 D697 E709 H710 D749 K750 A751 K752 F753 K910 R1062
BS03 ZN A C491 C501 C503 C506 C442 C452 C454 C457
BS04 ZN A C121 C127 C111 C117
BS05 ZN A H747 C750 C752 H695 C698 C700
BS06 ZN A C1018 C1414 C943 C975
Gene Ontology
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:7xc7, PDBe:7xc7, PDBj:7xc7
PDBsum7xc7
PubMed36302881
UniProtA0A0B0EGF3

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