Structure of PDB 7x88 Chain A

Receptor sequence
>7x88A (length=139) Species: 9606 (Homo sapiens) [Search protein sequence]
QCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVF
WLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYD
LFLNLEGNLNHLRCEKLTFNNPTTEFRYKLLRAGGVMVM
3D structure
PDB7x88 Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer.
ChainA
Resolution2.25 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H56 S58 F59 G77 Y78 A79 G80 F81 D103 F105 H53 S55 F56 G74 Y75 A76 G77 F78 D100 F102
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:7x88, PDBe:7x88, PDBj:7x88
PDBsum7x88
PubMed36272410
UniProtQ03111|ENL_HUMAN Protein ENL (Gene Name=MLLT1)

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