Structure of PDB 7x7a Chain A

Receptor sequence
>7x7aA (length=1241) Species: 237368 (Candidatus Scalindua brodae) [Search protein sequence]
DMNITVELTFFEPYRLVEWFDWDARKKSHSAMRGQAFAQWTWKGKGRTAG
KSFITGTLVRSAVIKAVEELLSLNNGKWEGVPCCNGSFQTDEKKPSFLRK
RHTLQWQANNKNICDKEEACPFCILLGRFDNAGKVHERNKDYDIHFSNFD
LDHKQEKNDLRLVDIASGRILNRVDFDTGKAKDYFRTWEADYETYGTYTG
RITLRNEHAKKLLLASLGFVDKLCGALCRIEVIHNDELRKQAEVIVEAFK
QNDKLEKIRILADAIRTLRLHGEGVIEKDELPDGKEERDKGHHLWDIKVQ
GTALRTKLKELWQSNKDIGWRKFTEMLGSNLYLIYKKETDTEYYSKASDL
FIPVTPPEGIETKEWIIVGRLKAATPFYFGVQQPSDSIPGKEKKSNEHTS
FNILLDKENRYRIPRSALRGALRRDLRTAFGSGCNVSLGGQILCNCKVCI
EMRRITLKDSVSDFSEPPEIRYRIAKNPGTATVEDGSLFDIEVGPEGLTF
PFVLRYRGHKFPEQLSSVIRYWEENDGKNGMAWLGGLDSTGKGRFALKDI
KIFEWDLNQKINEYIKERGMRGKEKELLEMGESSLPDGLIPYKFFEEREC
LFPYKENLKPQWSEVQYTIEVGSPLLTADTISALTEPGNRDAIAYKKRVY
NDGNNAIEPEPRFAVKSETHRGIFRTAVGRRTGDLGKEDHEDCTCDMCII
FGNEHESSKIRFEDLELINGNEFEKLEKHIDHVAIDRFTGGALDKAKFDT
YPLAGSPKKPLKLKGRFWIKKGFSGDHKLLITTALSDIRDGLYPLGSKGG
VGYGWVAGISIDDNVPDDFKEMINGPINNDYVHPGHQSPKQDHKNKNIYY
PHYFLDSGSKVYREKDIITHEEFTEELLSGKINCKLETLTPLIIPDTSDE
NGLKLQGNKPGHKNYKFFNINGELMIPGSELRGMLRTHFEALTKSCFAIF
GEDSTLSKTLGGKLDKALHPCTGLSDGLCPGCHLFGTTDYKGRVKFGFAK
YENGPEWLITRGNNPERSLTLGVLESPRPAFSIPDDESEIPGRKFYLHHN
GWRIIRQKQLEIRETVQPERNVTTEVMDKGNVFSFDVRFENLREWELGLL
LQSLDPGKNIAHKLGKGKPYGFGSVKIKIDSLHTFKINSNNDKIKRVPQS
DIREYINKGYQKLIEWSGVLPQWHVIPHIDKLYKLLWVPFLNDSKLEPDV
RYPVLNEESKGDYTYKKLGDKDNLPYKTRVKGLTTPWSPWN
3D structure
PDB7x7a Structure and function of a bacterial type III-E CRISPR-Cas7-11 complex.
ChainA
Resolution3.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A E16 R19 W23 R37 Q39 F41 T45 K47 K55 F57 T61 L62 R64 S65 S91 F92 Q93 T94 P102 S103 F104 L105 R106 R108 L133 G134 G140 K141 E144 H152 F153 S154 N155 D157 R176 I177 L178 N179 R180 V181 G186 K187 A188 D190 Y191 F192 R208 K229 G232 Y389 S391 G431 R472 R476 R480 R481 S494 L495 G496 G497 L500 R510 T513 L514 R530 I531 A532 K533 T539 V540 L545 F546 G592 G593 S596 T684 A685 T687 E725 T726 R728 G729 I730 R732 T733 G759 N760 E761 E763 S764 D788 H789 V790 A791 I792 R794 G797 G798 A799 K804 F805 S854 K855 Y922 P967 T969 S1001 E1002 R1004 R1008 I1021 G1421 T1422 T1423 Y1425 K1426 L1459 E1460 R1463 F1466 Y1481 K1551 G1552 K1553 P1554 Y1645 L1648 Y1663 E12 R15 W19 R33 Q35 F37 T41 K43 K51 F53 T57 L58 R60 S61 S87 F88 Q89 T90 P95 S96 F97 L98 R99 R101 L126 G127 G133 K134 E137 H145 F146 S147 N148 D150 R169 I170 L171 N172 R173 V174 G179 K180 A181 D183 Y184 F185 R201 K222 G225 Y343 S345 G380 R415 R419 R423 R424 S437 L438 G439 G440 L443 R453 T456 L457 R473 I474 A475 K476 T482 V483 L488 F489 G535 G536 S539 T627 A628 T630 E668 T669 R671 G672 I673 R675 T676 G702 N703 E704 E706 S707 D731 H732 V733 A734 I735 R737 G740 G741 A742 K747 F748 S797 K798 Y850 P895 T897 S929 E930 R932 R936 I949 G986 T987 T988 Y990 K991 L1024 E1025 R1028 F1031 Y1046 K1116 G1117 K1118 P1119 Y1202 L1205 Y1215
BS02 ZN A C501 C503 C506 C444 C446 C449
BS03 ZN A C88 C121 C130 C84 C114 C123
BS04 ZN A H747 C750 C752 C755 H690 C693 C695 C698
BS05 ZN A C1018 C1414 C946 C979
Gene Ontology
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7x7a, PDBe:7x7a, PDBj:7x7a
PDBsum7x7a
PubMed36302881
UniProtA0A0B0EGF3

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