Structure of PDB 7x4p Chain A

Receptor sequence
>7x4pA (length=306) Species: 1351 (Enterococcus faecalis) [Search protein sequence]
SKFSESTLSGWTKPASVTEEDRIENTISMIKSAIKNDNNFDNLVYEVFVQ
GSYGNNTNVRTNSDIDVNIMLTSTFYSKYPEGKTNSDYGFTDGTITYNEY
KNLILTALTNKFGTGNVTVGNKSIKITSNSYRVEADCIPSLLYRNYEYEN
SSSPNNYIEGIKYFASDNTSVVNYPKVHINNGIEKNNQTHKNYKRLVRVI
KRLRNKMTAENHFTNENITSFLIECLIWNVPNNYINDYDTWDETIKQTLI
FIKSSINDNSYKNWTEVSGMFYLFHNNRKWTSDDVSSFVNSLWSFMEYLE
HHHHHH
3D structure
PDB7x4p Crystal structure and functional implications of cyclic di-pyrimidine-synthesizing cGAS/DncV-like nucleotidyltransferases.
ChainA
Resolution1.6 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 UTP A G52 S53 D67 N174 S221 F222 G51 S52 D66 N173 S220 F221
BS02 U A D67 K123 I139 Y164 V172 N174 D66 K122 I138 Y163 V171 N173
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0016779 nucleotidyltransferase activity
GO:0046872 metal ion binding
Biological Process
GO:0009117 nucleotide metabolic process
GO:0051607 defense response to virus

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:7x4p, PDBe:7x4p, PDBj:7x4p
PDBsum7x4p
PubMed37604815
UniProtP0DX98|CDNE_ENTF2 Cyclic dipyrimidine nucleotide synthase CdnE (Gene Name=cdnE)

[Back to BioLiP]