Structure of PDB 7x0b Chain A

Receptor sequence
>7x0bA (length=300) Species: 68270 (Streptomyces spectabilis) [Search protein sequence]
SVRLADGKVRNPEGIEVNASLQCNMRCQSCAHLSPLYRRENADPAEIHDT
LSVLARSYHASYAKIMGGEPLLHPDVVGLIEAVRATGISDTVLVATNGTL
LHRATERFWQAVDSLEISVYPSRMIAPEEIERYRVLAREHGVSLLVNYYG
HFRAVYSESGTDAPDLVRDVFDTCKLAHFWNSHTVYDGWLYRCPQSVFMP
RQLRDGGWDPRVDGLRIEDDPAFLERLHRFLTADDPLRACRNCLGSVGKL
HPHQELPRAGWQVTEQLAALVDYPFLKVCKDDITADDGCVERSLSAPVGG
3D structure
PDB7x0b Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase.
ChainA
Resolution2.02028 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 SF4 A C24 M26 C28 C31 S35 G69 Y121 C23 M25 C27 C30 S34 G68 Y120
BS02 SF4 A C175 C194 Q196 L238 C241 C244 G246 C174 C193 Q195 L237 C240 C243 G245
BS03 SAM A S30 A32 H33 M67 G69 T97 N98 S119 Y121 Y150 F153 R154 S29 A31 H32 M66 G68 T96 N97 S118 Y120 Y149 F152 R153
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:7x0b, PDBe:7x0b, PDBj:7x0b
PDBsum7x0b
PubMed35622017
UniProtA8WEZ7

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