Structure of PDB 7wx6 Chain A

Receptor sequence

>7wx6A (length=267) Species: 446 (Legionella pneumophila) [Search protein sequence]

PRGSMITQVNQLDELQLKDLKTLRAECKKNDGSIPNLYIHILKQHRSLPT
SFLYYQNGALIGFLSIYFFAVEVAVLVSPQYRRQGIAKQLIKEALPLLIF
SCPSRLNDNWLTSKGFTYLHSEYFMERDDLNPILIRPLSFRMATLEDIPI
LCGLDEVCFPDSVHRFQQILNEREYEIVIAMLNNHPIGKSHIRWQTKRAT
LSDIAILPKEQGKGFGSALIAHCINMILSEGKSRVDLDVETHNKKALNLY
IQLGFHIQNACDYWSIN

3D structure

PDB

7wx6 Structural basis for the acetylation mechanism of the Legionella effector VipF.

Chain

Resolution

2.273 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	COA	A	V74 L75 V76 R81 R82 G84 I85 A86 K87 P110 L113 W117	V75 L76 V77 R82 R83 G85 I86 A87 K88 P103 L106 W110
BS02	COA	A	C167 F168 D216 I217 A218 I219 Q224 G225 G227 G229 S230 V252 Q265	C158 F159 D203 I204 A205 I206 Q211 G212 G214 G216 S217 V239 Q252
BS03	CLM	A	N32 L33 Y34 E129 F131 E253 Y276	N36 L37 Y38 E122 F124 E240 Y263

Gene Ontology

	Molecular Function
GO:0016747	acyltransferase activity, transferring groups other than amino-acyl groups

View graph for
Molecular Function

External links

PDB	RCSB:7wx6, PDBe:7wx6, PDBj:7wx6
PDBsum	7wx6
PubMed	36048151
UniProt	Q5C8M4

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