Structure of PDB 7wr5 Chain A

Receptor sequence
>7wr5A (length=424) Species: 623 (Shigella flexneri) [Search protein sequence]
RPDHCANTVKNFLRKSIAAQSYSKMFSQGTSFKSLNLSLEAPSGARSSFR
SLEHLDKVSRHYISEIIQKVHPLSSDERHLLSIIINSNFNFRHQSNSNLS
NNILNIKSFDKIQSENIQTHKNTYSEDIKEISNHDFVFFGVEISNHQEKL
PLNKTHHTVDFGANAYIIDHDSPYGYMTLTDHFDNAIPPVFYHEHQSFFL
DNFKEVVDEVSRYVHGNQGKTDVPIFNTKDMRLGIGLHLIDFIRKSKDQG
FREFCYNKNIDPVSLDRIINFVFQLEYHIPRMLSTDNFKKIKLRDISLED
AIKASNYEEINNKVTDKKMAHQALAYSLGNKKADIALYLLSKFNFTKQDV
AEMEKMKNNRYCNLYDVEYLLSKDGANYKVLEYFINNGLVDVNKKFQKVN
SGDTMLDNAMKSKDSKMIDFLLKN
3D structure
PDB7wr5 Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
ChainA
Resolution3.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.3.99.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5ZV A H143 Q144 S145 L149 I156 K157 I162 T169 N172 T173 F188 H206 F211 E326 H93 Q94 S95 L99 I106 K107 I112 T119 N122 T123 F138 H156 F161 E276
External links
PDB RCSB:7wr5, PDBe:7wr5, PDBj:7wr5
PDBsum7wr5
PubMed36624349
UniProtA0A0H2US87|OSPC3_SHIFL Arginine ADP-riboxanase OspC3 (Gene Name=ospC3)

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