Structure of PDB 7wqq Chain A

Receptor sequence
>7wqqA (length=228) Species: 9606 (Homo sapiens) [Search protein sequence]
TPEVGELIEKVRKAHQETFPALCQLGKYTTRVSLDIDLWDKFSELSTKCI
IKTVEFAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTF
SDGLTLNRTQMHHAGFGPLTDLVFAFANQLLPLEMDDAETGLLSAICLIC
GDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRS
ISAKGAERVITLKMEIPGSMPPLIQEML
3D structure
PDB7wqq Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling
ChainA
Resolution1.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A V240 K244 I254 K262 E412 V54 K58 I68 K76 E226
BS02 5Z6 A F228 S232 C235 L269 F286 S287 F302 F42 S46 C49 L83 F100 S101 F116
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0048384 retinoic acid receptor signaling pathway
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wqq, PDBe:7wqq, PDBj:7wqq
PDBsum7wqq
PubMed
UniProtP10276|RARA_HUMAN Retinoic acid receptor alpha (Gene Name=RARA)

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