Structure of PDB 7wnv Chain A

Receptor sequence
>7wnvA (length=224) Species: 9606 (Homo sapiens) [Search protein sequence]
ALSLTADQMVSALLDAEPPILYSEYDRPFSEASMMGLLTNLADRELVHMI
NWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNL
LLDRNQGKSVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGS
LEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMS
NKGMEHLYSMKCPLSDLLLEMLDA
3D structure
PDB7wnv Structure of the ligand binding domain of estrogen receptor alpha in complex with covalent inhibitor CO9
ChainA
Resolution2.3 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 2I9 A M343 L346 T347 A350 E353 W383 L387 L391 F404 I424 H524 L525 Y526 C530 M35 L38 T39 A42 E45 W75 L79 L83 F96 I116 H206 L207 Y208 C212
External links
PDB RCSB:7wnv, PDBe:7wnv, PDBj:7wnv
PDBsum7wnv
PubMed37871388
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

[Back to BioLiP]