Structure of PDB 7wnt Chain A

Receptor sequence
>7wntA (length=529) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence]
LPPPGPLTSGGLRVTALGGINEIGRNMTVFEHLGRLLIIDCGVLFPGHDE
PGVDLILPDMRHVEDRLDDIEALVLTHGHEDHIGAIPFLLKLRPDIPVVG
SKFTLALVAEKCREYRITPVFVEVREGQSTRHGVFECEYFAVNHSTPDAL
AIAVYTGAGTILHTGDIKFDQLPPDGRPTDLPGMSRLGDTGVDLLLCDST
NAEIPGVGPSESEVGPTLHRLIRGADGRVIVACFASNVDRVQQIIDAAVA
LGRRVSFVGRSMVRNMRVARQLGFLRVADSDLIDIAAAETMAPDQVVLIT
TGTQGEPMSALSRMSRGEHRSITLTAGDLIVLSSSLIPGNEEAVFGVIDA
LSKIGARVVTNAQARVHVSGHAYAGELLFLYNGVRPRNVMPVHGTWRMLR
ANAKLAASTGVPQESILLAENGVSVDLVAGKASISGAVPVGKMFVDGLIA
GDVGDITLGERLILSSGFVAVTPHLHSRGFSEDPKALEPAVRKVEAELES
LVIRIAQGVRRTVGKWVGETYRRQPMIVP
3D structure
PDB7wnt Structural ans functional study of RNase J from Mycobacterium tuberculosis
ChainA
Resolution2.44 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.5.2.6: beta-lactamase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H81 H83 H148 D170 H77 H79 H144 D166
BS02 ZN A D85 H86 D170 H397 D81 H82 D166 H393
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0004521 RNA endonuclease activity
GO:0004527 exonuclease activity
GO:0004534 5'-3' RNA exonuclease activity
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
GO:0046872 metal ion binding
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:7wnt, PDBe:7wnt, PDBj:7wnt
PDBsum7wnt
PubMed
UniProtP9WGZ9|RNJ_MYCTU Ribonuclease J (Gene Name=rnj)

[Back to BioLiP]