Structure of PDB 7wlp Chain A

Receptor sequence
>7wlpA (length=182) Species: 9606 (Homo sapiens) [Search protein sequence]
KESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHY
NKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSKKAKTRSSR
AGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAA
RDNKKTRIIPRHLQLAIRNDEELNKLLGKVTI
3D structure
PDB7wlp Epstein-Barr virus protein BKRF4 restricts nucleosome assembly to suppress host antiviral responses.
ChainA
Resolution2.29 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A S7 I8 Y11 I23 S24 S25 K26 M28 R159 S5 I6 Y9 I21 S22 S23 K24 M26 R157
BS02 peptide A T98 R99 S100 P108 V109 G110 T96 R97 S98 P106 V107 G108
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:7wlp, PDBe:7wlp, PDBj:7wlp
PDBsum7wlp
PubMed36067323
UniProtP20671|H2A1D_HUMAN Histone H2A type 1-D (Gene Name=H2AC7);
P23527

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