Structure of PDB 7wku Chain A

Receptor sequence
>7wkuA (length=304) Species: 1586324 (Porcine deltacoronavirus) [Search protein sequence]
AGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGDQ
WTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPDY
KFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGYT
LKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYYT
DNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTNM
SYIMGLSQTARVPVERILNTIIQLTTNRDGACIMGSYDFECDWTPEMVYN
QAPI
3D structure
PDB7wku The Structure of the Porcine Deltacoronavirus Main Protease Reveals a Conserved Target for the Design of Antivirals.
ChainA
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
3.4.19.12: ubiquitinyl hydrolase 1.
3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A H41 F139 G142 C144 H162 H163 I164 E165 F166 N167 D186 E188 I190 H41 F139 G142 C144 H162 H163 I164 E165 F166 N167 D186 E188 I190
BS02 peptide A S25 A26 L27 S25 A26 L27
BS03 peptide A Q223 Q225 R266 Q223 Q225 R266
Gene Ontology
Molecular Function
GO:0008233 peptidase activity
Biological Process
GO:0019082 viral protein processing

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Molecular Function
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Biological Process
External links
PDB RCSB:7wku, PDBe:7wku, PDBj:7wku
PDBsum7wku
PubMed35336895
UniProtA0A140ESF0

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