Structure of PDB 7wjl Chain A

Receptor sequence
>7wjlA (length=453) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
AQIPESAKAVVVLSPYSLQHVFPREWVTKSYRKTIVERPERLLASSMGIS
AAITMYPSLFTLKSSHQRKGSLMAPHVLKVHGSSWPAELIELCQMADAKL
LKGEIEVPDTWNSGDIYLSSKTIKALQGTIGAIETGVDSIFKGPSAEHIS
NRAFVAIRPPGHHCHYGTPSGFCLLNNAHVAIEYAYDTYNVTHVVVLDFD
LHHGDGTQDICWKRAGFKPEEEPEDSSYDDFGKKFAEFPKVGYFSMHDIN
SFPTESGFATKENIKNASTCIMNSHDLNIWNIHLSKWTTEEEFNVLYRTK
YRTLFAKADEFFRSAKLEMNQQGRPFKGLVVISAGFDASEFEQTHSVNVP
TSFYTTFTKDALKLAQMHCHGKVLSLMEGGYSDKAICSGVFAHLIGLQNQ
DWVKEWGSEQVVKEIVRGCKPAWKPYDVIRIWAEEVIRLGRAMIPEFDDI
IFK
3D structure
PDB7wjl Structural characterization of fungus-specific histone deacetylase Hos3 provides insights into developing selective inhibitors with antifungal activity.
ChainA
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.5.1.98: histone deacetylase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H195 D233 H235 H162 D200 H202
External links
PDB RCSB:7wjl, PDBe:7wjl, PDBj:7wjl
PDBsum7wjl
PubMed35623387
UniProtQ02959|HOS3_YEAST Histone deacetylase HOS3 (Gene Name=HOS3)

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