Structure of PDB 7wit Chain A

Receptor sequence
>7witA (length=1133) Species: 9913,10036 [Search protein sequence]
LQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLC
VAFDAQARKGARAIWRALCHAFGRRLILSSTFRILADLLGFAGPLCIFGI
VDHLGKEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQT
KIYNKIMHLSTSNTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGV
ILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEHSNERLKQT
NEMLRGMKLLKLYAWESIFCSRVEVTRRKEMTSLRAFAVYTSISIFMNTA
IPIAAVLITFVGHVSFFKESDLSPSVAFASLSLFHILVTPLFLLSSVVRS
TVKALVSVQKLSEFLSSCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTM
IVGQVGCGKSSLLLATLGEMQKVSGAVFWGPVAYASQKPWLLNATVEENI
TFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGERGINLSGGQRQRI
SVARALYQQTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVT
HKLQYLPHADWIIAMKDGTIQREGTLKDFQRSEPWRACTKYLSSAGILLL
SLLVFSQLLKHMVLVAIDYWLAKWTDDQSVYAMVFTLLCSLGIVLCLVTS
VTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTID
QHIPSTLECLSRSTLLCVSALTVISYVTPVFLVALLPLAVVCYFIQKYFR
VASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDS
NNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGL
GLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHALLKTEAESYPDQGKIQ
IQNLSVRYDSSLKPVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMV
DMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKC
SDSTLWEALEIAQLKLVVKALPGGLDAIITEGGENFSQGQRQLFCLARAF
VRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSA
DLVMVLKRGAILEFDKPETLLSQKDSVFASFVR
3D structure
PDB7wit Structural Insights Into the High Selectivity of the Anti-Diabetic Drug Mitiglinide
ChainA
Resolution3.21 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A S405 W688 G716 C717 G718 K719 S720 S721 S162 W378 G406 C407 G408 K409 S410 S411
BS02 9I0 A I381 W430 S1238 N1245 R1246 R1300 I138 W181 S805 N812 R813 R867
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0008281 sulfonylurea receptor activity
GO:0016887 ATP hydrolysis activity
GO:0140359 ABC-type transporter activity
Biological Process
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wit, PDBe:7wit, PDBj:7wit
PDBsum7wit
PubMed35847046
UniProtA0A1U7R319;
A2VDS4

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