Structure of PDB 7wd3 Chain A

Receptor sequence
>7wd3A (length=723) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence]
KLPAEFITRPHPSKDHGKETCTAYIHPNVLSSLEINPGSFCTVGKIGENG
ILVIARAGDEEVHPVNVITLSTTIRSVGNLILGDRLELKKAQVQPPYATK
VTVGSLQGYNILECMEEKVIQKLLDDSGVIMPGMIFQNLKTKAGDESIDV
VITDAFYLSPPFIFRKGSTHITFSKETQANRKYNLPEPLSYAAVGGLDKE
IESLKSAIEIPLHQPTLFSSFGVSPPRGILLHGPPGTGKTMLLRVVANTS
NAHVLTINGPSIVSKYLGETEAALRDIFNEARKYQPSIIFIDEIDSIAPN
RANDDSGEVESRVVATLLTLMDGMGAAGKVVVIAATNRPNSVDPALRRPG
RFDQEVEIGIPDVDARFDILTKQFSRMSSDRHVLDSEAIKYIASKTHGYV
GADLTALCRESVMKTIQRGLGTDANIDKFSLKVTLKDVESAMVDIRPSAM
REIFLEMPKVYWSDIGGQEELKTKMKEMIQLPLEASETFARLGISAPKGV
LLYGPPGCSKTLTAKALATESGINFLAVKGPEIFNKYVGESERAIREIFR
KARSAAPSIIFFDEIDALSPDRDGSSTSAANHVLTSLLNEIDGVEELKGV
VIVAATNRPDEIDAALLRPGRLDRHIYVGPPDVNARLEILKKCTKKFNTE
ESGVDLHELADRTEGYSGAEVVLLCQEAGLAAIMEDLDVAKVELRHFEKA
FKGIARGITPEMLSYYEEFALRS
3D structure
PDB7wd3 Structural dynamics of AAA + ATPase Drg1 and mechanism of benzo-diazaborine inhibition.
ChainA
Resolution3.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.4.10: non-chaperonin molecular chaperone ATPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ATP A G289 T290 G291 K292 T293 M294 G454 A455 T458 G236 T237 G238 K239 T240 M241 G401 A402 T405
BS02 NDT A M294 Q426 R429 T458 M241 Q373 R376 T405
BS03 ATP A G560 C561 S562 E617 I692 G721 G507 C508 S509 E564 I639 G668
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009410 response to xenobiotic stimulus
GO:0034214 protein hexamerization
GO:0042254 ribosome biogenesis
GO:0042273 ribosomal large subunit biogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0030687 preribosome, large subunit precursor

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7wd3, PDBe:7wd3, PDBj:7wd3
PDBsum7wd3
PubMed36351914
UniProtP32794|AFG2_YEAST ATPase family gene 2 protein (Gene Name=AFG2)

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