Structure of PDB 7w6z Chain A

Receptor sequence
>7w6zA (length=414) Species: 523791 (Kangiella koreensis DSM 16069) [Search protein sequence]
MTDFLYSIFGLLILLGVLVTFHEWGHYWVAKKLGVKALRFSVGFGKPIWG
RTNKHGTEFVIAPIPLGGYVRFVDEREGEVAEADLPFAFNRQQVWKRILI
VLAGPMANFLLAIVVYAAVYMMGIAVGKPFVTNVLPNTVAAQANFPENSE
ILSVDGVQVKSLEDAIFAFVDHIDDDKTIKVVVKPLNQEPTTVVLDVSQW
QEPDEGTIFDSLGLGFGRVNGEPSLGLVAKDSPAEKGGLKVGDTVVSVNG
ESISLWSEFVSFIENNPGKPLELIVARDGYQQPLVVTPEANERDRTIGYL
GISPAFQGYNVINYGFFESFGKGAEQTWVMVERIGSFLGKLITAQAGMVA
FLLYLAMISVNLGFVNLLPIPMLDGGHLMYYLVELVGIILVLTIMAIALF
FDINRINQLESSFQ
3D structure
PDB7w6z Mechanistic insights into intramembrane proteolysis by E. coli site-2 protease homolog RseP.
ChainA
Resolution3.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.24.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN A H22 H26 D395 H22 H26 D374
BS02 BAT A V19 H22 E23 H26 F44 L66 G68 N387 L394 D395 V19 H22 E23 H26 F44 L66 G68 N366 L373 D374
Gene Ontology
Molecular Function
GO:0004222 metalloendopeptidase activity
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7w6z, PDBe:7w6z, PDBj:7w6z
PDBsum7w6z
PubMed36001659
UniProtC7R5Z1

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