Structure of PDB 7w6j Chain A

Receptor sequence
>7w6jA (length=177) Species: 9606 (Homo sapiens) [Search protein sequence]
SRVLLALHDRAPQLKISDDRLTVVGEKGYSMVRASHGVRKGAWYFEITVD
EMPPDTAARLGWSQPLGNLQAPLGYDKFSYSWRSKKGTKFHQSIGKHYSS
GYGQGDVLGFYINLPESSEIIFYKNGVNQGVAYKDIFEGVYFPAISLYKS
CTVSINFGPCFKYPPKDLTYRPMSDMG
3D structure
PDB7w6j Structural basis for product specificities of MLL family methyltransferases.
ChainA
Resolution2.68 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R323 L350 R39 L66
Gene Ontology
Cellular Component
GO:0048188 Set1C/COMPASS complex

View graph for
Cellular Component
External links
PDB RCSB:7w6j, PDBe:7w6j, PDBj:7w6j
PDBsum7w6j
PubMed36108631
UniProtQ9UBL3|ASH2L_HUMAN Set1/Ash2 histone methyltransferase complex subunit ASH2 (Gene Name=ASH2L)

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