Structure of PDB 7w2j Chain A

Receptor sequence

>7w2jA (length=537) Species: 376620 (Gluconobacter japonicus)

LSADVVIIGAGICGSLLAHKLVRNGLSVLLLDAGPRRDRSQIVENWRNMP
PDNKSQYDYATPYPSVPWAPHTNYFPDNNYLIVKGPDRTAYKQGIIKGVG
GTTWHWAASSWRYLPNDFKLHSTYGVGRDYAMSYDELEPYYYEAECEMGV
MGPNGEEITPSAPRQNPWPMTSMPYGYGDRTFTEIVSKLGFSNTPVPQAR
NSRPYDGRPQCCGNNNCMPICPIGAMYNGVYAAIKAEKLGAKIIPNAVVY
AMETDAKNRITAISFYDPDKQSHRVVAKTFVIAANGIETPKLLLLAANDR
NPHGIANSSDLVGRNMMDHPGIGMSFQSAEPIWAGGGSVQMSSITNFRDG
DFRSEYAATQIGYNNTAQNSRAGMKALSMGLVGKKLDEEIRRRTAHGVDI
YANHEVLPDPNNRLVLSKDYKDALGIPHPEVTYDVGEYVRKSAAISRQRL
MDIAKAMGGTEIEMTPYFTPNNHITGGTIMGHDPRDSVVDKWLRTHDHSN
LFLATGATMAASGTVNSTLTMAALSLRAADAILNDLK

3D structure

• PDB: 7w2j Structural and Bioelectrochemical Elucidation of Direct Electron Transfer-type Membrane-bound Fructose Dehydrogenase
• Chain: A
• Resolution: 3.6 Å

Enzymatic activity

• Enzyme Commision number: 1.1.5.14: fructose 5-dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	FAD	A	G14 G16 D37 A38 Y64 K102 G106 T107 T108 H110 W111 S114 V254 A289 N290 E293 K296 L297 N477 N521 S522 T523	G9 G11 D32 A33 Y59 K97 G101 T102 T103 H105 W106 S109 V249 A284 N285 E288 K291 L292 N472 N516 S517 T518
BS02	F3S	A	R205 C216 G218 N219 N220 C222 C226 I228 A230 S343	R200 C211 G213 N214 N215 C217 C221 I223 A225 S338

Gene Ontology

Molecular Function

• GO:0016491 oxidoreductase activity
• GO:0016614 oxidoreductase activity, acting on CH-OH group of donors
• GO:0047904 fructose 5-dehydrogenase activity
• GO:0050660 flavin adenine dinucleotide binding

Biological Process

• GO:0006000 fructose metabolic process

Cellular Component

• GO:0005886 plasma membrane

External links

• PDB: RCSB:7w2j, PDBe:7w2j, PDBj:7w2j
• PDBsum: 7w2j
• UniProt: M1VMF7|FDHL_GLUJA Fructose dehydrogenase large subunit (Gene Name=fdhL)