Structure of PDB 7w1i Chain A

Receptor sequence
>7w1iA (length=497) Species: 2021 (Thermobifida fusca) [Search protein sequence]
MEIVIRTGSGDVRGSKENGIAVFRGIPYAEPPVGAHRFTAPRPPRPWDGV
RDATEFSATAPRPPYPEAIGALLIERFIPGDDYLTLNVWTPDPNAVGLPV
MVWIHGGAFTNGSGSEPVYDGAAFARDGVVFVSFNYRLGIIGFADLPDAP
SNRGLLDQIAALEWVRDNIARFGGDPGNVTVFGESAGAMSVCTLMATPRA
RGLFRRAILQSGAGNMAVAAEDATTIAAVIAHRLGVEPTAAALAHVPVAQ
LLDVQQQVAQEIQGAPDPAVWGERIAGGSVLLPFAPVIDGELLSQRPAEA
IAGGAGHDVDLLFGTTTDLYRLFLAPTGLLPFITSDYVTAHLAKSGLDAD
AAKAYTAEGRGEEPGDILASIITDQVFRIPALRIAESRVDAPARTFGYEF
AWRTPQLDGILGACHAVELPFVFRTLDRAASLVGTNPPEELAETVHNAWV
RFATSGDPGWPAWNPETRSVMRFDHPVSEMVTDPYPATRALWDGVPL
3D structure
PDB7w1i Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization
ChainA
Resolution1.67 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.1: carboxylesterase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 C8X A G106 G107 A108 E184 S185 A186 L282 F323 F377 H415 G106 G107 A108 E184 S185 A186 L282 F323 F377 H415
BS02 C9C A L72 I74 V118 A416 R428 A429 A430 S431 L432 L72 I74 V118 A416 R428 A429 A430 S431 L432
Gene Ontology
Molecular Function
GO:0017171 serine hydrolase activity
GO:0052689 carboxylic ester hydrolase activity
GO:0106435 carboxylesterase activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:7w1i, PDBe:7w1i, PDBj:7w1i
PDBsum7w1i
PubMed
UniProtP86325|EST1_THEFU Carboxylesterase

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