Structure of PDB 7vze Chain A

Receptor sequence
>7vzeA (length=89) Species: 9606 (Homo sapiens) [Search protein sequence]
LVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRLNEGD
QVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRP
3D structure
PDB7vze Structural and biochemical analysis of the PTPN4 PDZ domain bound to the C-terminal tail of the human papillomavirus E6 oncoprotein.
ChainA
Resolution2.882 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide A R527 F528 G529 F530 N531 V532 K533 Q538 H579 D580 R13 F14 G15 F16 N17 V18 K19 Q24 H65 D66
External links
PDB RCSB:7vze, PDBe:7vze, PDBj:7vze
PDBsum7vze
PubMed35089587
UniProtP29074|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)

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