Structure of PDB 7vuk Chain A

Receptor sequence
>7vukA (length=421) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence]
MRDVLEVLEFPRVRALLAERAKTPLGRELALALAPLPREEAEKRHELTGE
ALSYPYALPEAGTLREAYGRALAGARLSGPELLKAAKALEEAMALKEELL
PLKNALSQVAEGIGDHTPFLERVRKALDEEGAVKDEASPRLAQIRRELRP
LRQQILKLNNRLQALRLKEEEEVNRILRDLSERLAKDEGVPKTLEALGLL
DLVQAQAALARDLGLSRPAFGERYELYRAFHPLIPDAVRNSFALDEKNRI
LLISGPNMGGKTALLKTLGLAVLMAQSGLFVAAEKALLAWPDRVYADIGD
LQENLSTFAGHLRRLREMLEEATSHSLVLIDELGSGTDPEEGAALSQAIL
EALLERGVKGMVTTHLSPLKAFAQGREGIQNASMRFDALRPTYELVLGVP
SYALAIARRLALPEEVLKRAE
3D structure
PDB7vuk Structural and functional insights into the mechanism by which MutS2 recognizes a DNA junction.
ChainA
Resolution3.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP A I294 A297 V298 N317 M318 G319 G320 K321 T322 A323 Y458 I234 A237 V238 N257 M258 G259 G260 K261 T262 A263 Y393
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0030983 mismatched DNA binding
Biological Process
GO:0006298 mismatch repair

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Molecular Function
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Biological Process
External links
PDB RCSB:7vuk, PDBe:7vuk, PDBj:7vuk
PDBsum7vuk
PubMed35439431
UniProtQ5SHT5|MUTS2_THET8 Endonuclease MutS2 (Gene Name=mutS2)

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