Structure of PDB 7vto Chain A

Receptor sequence
>7vtoA (length=262) Species: 9606 (Homo sapiens) [Search protein sequence]
LRSIVKIGQGASGTVYTAMDVATGQEVAIKQPKKELIINEILVMRENKNP
NIVNYLDSYLWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFL
HSNQVIHRNIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYW
MAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNG
TPELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSL
TPLIAAAKEATK
3D structure
PDB7vto The crystal structure of PAK1 with the inhibitor GW8510
ChainA
Resolution2.59 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 107 A I276 M344 E345 Y346 L347 L396 K538 I7 M64 E65 Y66 L67 L116 K258
Gene Ontology
Molecular Function
GO:0004672 protein kinase activity
GO:0005524 ATP binding
Biological Process
GO:0006468 protein phosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:7vto, PDBe:7vto, PDBj:7vto
PDBsum7vto
PubMed
UniProtQ13153|PAK1_HUMAN Serine/threonine-protein kinase PAK 1 (Gene Name=PAK1)

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