Structure of PDB 7vsr Chain A

Receptor sequence
>7vsrA (length=290) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
YCLEDALNDLFIPETTIETILKRLTIKKNIILQGPPGVGKTFVARRLAYL
LTGEKAPQRVNMVQFHQSYSYEDFIQGYRPNGVGFRRKDGIFYNFCQQAK
EQPEKKYIFIIDEINRANLSKVFGEVMMLMEHDKRGENWSVPLTYSENDE
ERFYVPENVYIIGLMNTADRSLAVVDYALRRRFSFIDIEPGFDTPQFRNF
LLNKKAEPSFVESLCQKMNELNQEISKEATILGKGFRIGHSYFCCGLEDG
TSPDTQWLNEIVMTDIAPLLEEYFFDDPYKQQKWTNKLLG
3D structure
PDB7vsr Structure-based mechanism for activation of the AAA+ GTPase McrB by the endonuclease McrC.
ChainA
Resolution4.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.21.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP A D176 P203 G204 V205 G206 K207 T208 F209 H407 S408 D9 P36 G37 V38 G39 K40 T41 F42 H240 S241
BS02 MG A T208 D279 T41 D112
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003924 GTPase activity
GO:0004519 endonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0010385 double-stranded methylated DNA binding
GO:0016887 ATP hydrolysis activity
GO:0042802 identical protein binding
GO:0044729 hemi-methylated DNA-binding
Biological Process
GO:0009307 DNA restriction-modification system
Cellular Component
GO:1905348 endonuclease complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:7vsr, PDBe:7vsr, PDBj:7vsr
PDBsum7vsr
PubMed
UniProtP15005|MCRB_ECOLI Type IV methyl-directed restriction enzyme EcoKMcrB subunit (Gene Name=mcrB)

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