Structure of PDB 7vrq Chain A

Receptor sequence
>7vrqA (length=114) Species: 9606 (Homo sapiens) [Search protein sequence]
GSHMQDPEQLKHCNGILKELLSKKHAAYAWPFYKPVDASALGLHDYHDII
KHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYEYNPPDHDVVAMAR
KLQDVFEFRYAKMP
3D structure
PDB7vrq Structural and biochemical insights into purine-based drug molecules in hBRD2 delineate a unique binding mode opening new vistas in the design of inhibitors of the BET family.
ChainA
Resolution1.15 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 37T A P371 V376 N429 P31 V36 N89
External links
PDB RCSB:7vrq, PDBe:7vrq, PDBj:7vrq
PDBsum7vrq
PubMed37432115
UniProtP25440|BRD2_HUMAN Bromodomain-containing protein 2 (Gene Name=BRD2)

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