Structure of PDB 7vqp Chain A

Receptor sequence
>7vqpA (length=231) Species: 10116 (Rattus norvegicus) [Search protein sequence]
KLSEEQQHIIAILLDAHHKTYDPDFRPPVPLSMLPHLADLVSYSIQKVIG
FAKMIPGFRDLTSDDQIVLLKSSAIEVIMLRSNQSFTMDDMSWDCGSQDY
KYDVTDVSKAGHTLELIEPLIKFQVGLKKLNLHEEEHVLLMAICIVSPDR
PGVQDAKLVEAIQDRLSNTLQTYIRCRHPPPGSHQLYAKMIQKLADLRSL
NEEHSKQYRSLSFQPENSMKLTPLVLEVFGN
3D structure
PDB7vqp Lithocholic Acid Amides as Potent Vitamin D Receptor Agonists.
ChainA
Resolution1.94 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide A I238 K242 S252 Q255 I256 K260 P412 E416 I49 K53 S63 Q66 I67 K71 P223 E227
BS02 7SW A Y143 D144 K236 R270 S271 W282 C284 H301 H393 Y21 D22 K47 R81 S82 W93 C95 H112 H204
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:7vqp, PDBe:7vqp, PDBj:7vqp
PDBsum7vqp
PubMed35053278
UniProtP13053|VDR_RAT Vitamin D3 receptor (Gene Name=Vdr)

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