Structure of PDB 7vli Chain A

Receptor sequence
>7vliA (length=38) Species: 64320 (Zika virus) [Search protein sequence]
DMYIERAGDITWEKDAEVTGNSPRLDVALDESGDFSLV
3D structure
PDB7vli Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors.
ChainA
Resolution2.385 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.1.1.56: mRNA (guanine-N(7))-methyltransferase.
2.1.1.57: methyltransferase cap1.
2.7.7.48: RNA-directed RNA polymerase.
3.4.21.91: flavivirin.
3.6.1.15: nucleoside-triphosphate phosphatase.
3.6.4.13: RNA helicase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 7QG A D83 F84 D34 F35
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Cellular Component
GO:0044423 virion component

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:7vli, PDBe:7vli, PDBj:7vli
PDBsum7vli
PubMed35475620
UniProtQ32ZE1|POLG_ZIKV Genome polyprotein

[Back to BioLiP]