Structure of PDB 7vb3 Chain A

Receptor sequence
>7vb3A (length=408) Species: 4006 (Linum usitatissimum) [Search protein sequence]
GVITCKAIMLKEAKLPGMSYADTVQIIDIQVDPPQNVELRVKMLCASVCR
TDILTIEGFMAPTQFPKINGHEGVGIIESMGPDTKNFKVGDVIVAPTLGE
CQTCSSCRSGRTNFCQNYGANESALEPDGTSRFSYIDSDGKKKLLYYKLG
CSTWTQYMVVDSNYATKLNEIAPELPPPHGSILSCAFATGYGAVWLDAAV
QEGDSVAIFGVGSVGISAVIAAKELKAKQIIVVDRNEYKLKMAMELGATH
CINSEKLPEGVTPSQAVRKLTPKEVGVDASIESSGYDVFMNEAMKAAIHG
KAKTVITGEGIYENDRIFFDFKDFLFGGNVVGNVTGRVRIHSDFPGLLRK
AQEPVIRAGMDKILGYDAATMKCKYEVDIREGTPALLKALEEVENVDCVK
LVIKLNDY
3D structure
PDB7vb3 Structural characterization of Linum usitatissimum hydroxynitrile lyase: A new cyanohydrin decomposition mechanism involving a cyano-zinc complex.
ChainA
Resolution1.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 4.1.2.46: aliphatic (R)-hydroxynitrile lyase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 NAD A C63 R64 T65 C199 T203 G226 V228 D248 R249 S297 S298 G299 Y300 F303 T321 E323 V348 C49 R50 T51 C185 T189 G212 V214 D234 R235 S283 S284 G285 Y286 F289 T307 E309 V334
BS02 ZN A C115 C118 C121 C129 C101 C104 C107 C115
BS03 ZN A C63 H85 C199 C49 H71 C185
BS04 MG A E52 E140 E38 E126
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0016829 lyase activity
GO:0046872 metal ion binding
GO:0051903 S-(hydroxymethyl)glutathione dehydrogenase [NAD(P)+] activity
GO:0052919 aliphatic (R)-hydroxynitrile lyase activity
Biological Process
GO:0046294 formaldehyde catabolic process
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:7vb3, PDBe:7vb3, PDBj:7vb3
PDBsum7vb3
PubMed35101448
UniProtP93243|AHNL_LINUS Aliphatic (R)-hydroxynitrile lyase

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