Structure of PDB 7v38 Chain A

Receptor sequence
>7v38A (length=203) Species: 11622 (Lassa virus Josiah) [Search protein sequence]
AGLTYSQLMTLKDAMLQLDPNAKTWMDIEGRPEDPVEIALYQPSSGCYIH
FFREPTDLKQFKQDAKYSHGIDVTDLFATQPGLTSAVIDALPRNMVITCQ
GSDDIRKLLESQGRKDIKLIDIALSKTDSRKYENAVWDQYKDLCHMHTGV
VVEKKKEEITPHCALMDCIMFDAAVSGGLNTSVLRAVLPRDMVFRTSTPR
VVL
3D structure
PDB7v38 Targeted Covalent Inhibitors Allosterically Deactivate the DEDDh Lassa Fever Virus NP Exonuclease from Alternative Distal Sites.
ChainA
Resolution2.403 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.13.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN A E399 C506 H509 C529 E37 C144 H147 C163
BS02 PMB A Q379 C409 R551 A552 Q17 C47 R185 A186
External links
PDB RCSB:7v38, PDBe:7v38, PDBj:7v38
PDBsum7v38
PubMed34977900
UniProtP13699|NCAP_LASSJ Nucleoprotein (Gene Name=N)

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