Structure of PDB 7uzx Chain A

Receptor sequence
>7uzxA (length=204) Species: 176279 (Staphylococcus epidermidis RP62A) [Search protein sequence]
YSKIKISGTIEVVTGLHIGGGGSPVVRDLQTKLPIIPGSSIKGKMRNLLA
KHFGLKMKQESHNQDDERVLRLFGSSEKGNIQRARLQISDAFFSEKTKEH
FAQNDIAYTETKFENTINRLTAVANPRQIERVTRGSEFDFVFIYNVDEES
QVEDDFENIEKAIHLLENDYLGGGGTRGNGRIQFKDTNIETVVGEYDSTN
LKIK
3D structure
PDB7uzx Structures of an active type III-A CRISPR effector complex.
ChainA
Resolution3.49 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna A I19 G20 G21 G23 P47 S49 S50 K52 G53 R56 S85 S86 E87 N125 T126 I127 P136 R137 Y180 G183 T186 R187 I18 G19 G20 G22 P37 S39 S40 K42 G43 R46 S75 S76 E77 N115 T116 I117 P126 R127 Y170 G173 T176 R177
BS02 rna A V133 A134 P136 V123 A124 P126
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:7uzx, PDBe:7uzx, PDBj:7uzx
PDBsum7uzx
PubMed35714601
UniProtQ5HK91

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