Structure of PDB 7uyn Chain A

Receptor sequence
>7uynA (length=248) Species: 11801 (Moloney murine leukemia virus) [Search protein sequence]
TWLSDFPQAWAETGGMGLAVRQAPLIIPLKATSTPVSIKQYPMSQEARLG
IKPHIQRLLDQGILVPCQSPWNTPLLPVYRPVQDLREVNKRVEDIHPTVP
NPYNLLSGLPPSHQWYTVLDLKDAFFCLRLHPTSQPLFAFEWRDPEMGIS
GQLTWTRLPQGFKNSPTLFDEALHRDLADFRIQHPDLILLQYVDDLLLAA
TSELDCQQGTRALLQTLGNLGYRASAKKAQICQKQVKYLGYLLKEGQR
3D structure
PDB7uyn Crystal structures of B-form Alien DNA
ChainA
Resolution1.65 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.26.4: ribonuclease H.
3.4.23.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna A Y64 L99 P100 R116 K120 Y41 L76 P77 R86 K90
BS02 dna A L99 D114 L115 R116 G191 L76 D84 L85 R86 G161
External links
PDB RCSB:7uyn, PDBe:7uyn, PDBj:7uyn
PDBsum7uyn
PubMed36633282
UniProtP03355|POL_MLVMS Gag-Pol polyprotein (Gene Name=gag-pol)

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